Magnotriol B
Magnotriol B is a cholinesterase inhibitor with IC50 values of 12.63 nM and 14.5 nM against AChE and BChE, respectively. Magnotriol B also exhibits significant NO inhibitory activity with an IC50 of 2.02 μM. Magnotriol B can be used in the research of neurodegenerative and inflammatory diseases[1][2].
Product Specifications
CAS Number
92829-71-5
UNSPSC
12352005
Target
Cholinesterase (ChE)
Related Pathways
Neuronal Signaling
Field of Research
Inflammation/Immunology; Neurological Disease
Smiles
OC1=CC=C(C(C2=CC(CC=C)=C(O)C=C2)=C1)O
Molecular Formula
C15H14O3
Molecular Weight
242.27
References & Citations
[1]Zhang B, et al. Four new honokiol derivatives from the stem bark of Magnolia officinalis and their anticholinesterase activities. Phytochemistry Letters, 2019, 29: 195-198.|[2]Nie W, et al. Biphenyl-type neolignans with NO inhibitory activity from the fruits of Magnolia tripetala. Phytochemistry Letters, 2021, 44: 222-226.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
AChE; BChE
Frequently Asked Questions
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