Luteolin-7-O-β-D-glucuronide methyl ester

Luteolin-7-O-β-D-glucuronide methyl ester is a flavonoid with antioxidative activity. Luteolin-7-O-β-D-glucuronide methyl ester exhibits potent antioxidative activity with an IC50 of 3.05 μg/mL in the NBT superoxide scavenging assay. Luteolin-7-O-β-D-glucuronide methyl ester inhibits LDL oxidation induced by Cu2+ with the IC50 value is 71.13 μg/mL[1][2].

Product Specifications

CAS Number

[76939-42-9]

UNSPSC

12352005

Target

LDLR

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Metabolic Disease; Cardiovascular Disease

Smiles

O=C1C2=C(O)C=C(O[C@@H]3O[C@@H]([C@H]([C@@H]([C@H]3O)O)O)C(OC)=O)C=C2OC(C4=CC(O)=C(C=C4)O)=C1

Molecular Formula

C22H20O12

Molecular Weight

476.39

References & Citations

[1]Woo ER, et al. Antioxidative constituents from Lycopus lucidus. Arch Pharm Res. 2004 Feb;27 (2) :173-6. |[2]Lee MJ, et al. Protective effects of luteolin-7-O-beta-D-glucuronide methyl ester from the ethyl acetate fraction of Lycopi Herba against pro-oxidant reactive species and low-density lipoprotein peroxidation. J Enzyme Inhib Med Chem. 2010 Oct;25 (5) :702-7.