Cassiaside C2
Cassiaside C2 is a naphthopyrone with a strong antiallergic activity. Cassiaside C2 inhibits the histamine release from rat peritoneal exudate mast cells induced by antigen-antibody reaction[1][2].
Product Specifications
CAS Number
218155-49-8
UNSPSC
12352005
Target
Histamine Receptor
Related Pathways
GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Smiles
OC1=C(C(OC(C)=C2)=O)C2=CC3=C1C(O[C@@H]4O[C@@H]([C@H]([C@@H]([C@H]4O)O)O)CO[C@H]5[C@@H]([C@H]([C@@H]([C@H](O5)CO)O)O[C@@H]6O[C@@H]([C@H]([C@@H]([C@H]6O)O)O)CO[C@@H]7O[C@@H]([C@H]([C@@H]([C@H]7O)O)O)CO)O)=CC(OC)=C3
Molecular Formula
C39H52O25
Molecular Weight
920.82
References & Citations
[1]Zhang Z, et al. Total synthesis of the antiallergic naphtho-alpha-pyrone tetraglucoside, cassiaside C (2), isolated from cassia seeds. J Org Chem. 2003 Aug 8;68 (16) :6309-13. |[2]Kitanaka S, et al. Antiallergic agent from natural sources. Structures and inhibitory effect of histamine release of naphthopyrone glycosides from seeds of Cassia obtusifolia L. Chem Pharm Bull (Tokyo) . 1998 Oct;46 (10) :1650-2.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Frequently Asked Questions
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