Torulene

Torulene (Torulin) is an orally active carotenoid with anti-cancer activity. Torulene inhibits proliferation and induces apoptosis of tumor cells via a mitochondrial signal pathway and the down-regulation of androgen receptor (AR) expression. Torulene can be used for the study of prostate cancer[1][2].

Product Specifications

CAS Number

[547-23-9]

Product Name Alternative

Torulin

UNSPSC

12352211

Target

Androgen Receptor; Apoptosis; Bcl-2 Family; MMP

Related Pathways

Apoptosis; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Smiles

C/C(C)=C/C=C/C(C)=C/C=C/C(C)=C/C=C/C(C)=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CCCC1(C)C

Molecular Formula

C40H54

Molecular Weight

534.86

References & Citations

[1]Du C, et al. The suppression of torulene and torularhodin treatment on the growth of PC-3 xenograft prostate tumors. Biochem Biophys Res Commun. 2016 Jan 22;469 (4) :1146-52.|[2]Chao Du, et al. The suppression of torulene and torularhodin treatment on the growth of PC-3 xenograft prostate tumors, Biochemical and Biophysical Research Communications, Volume 469, Issue 4,2016, Pages 1146-1152, ISSN 0006-291X