Azafrin
Azafrin, a carotenoid, is one of the most abundant active ingredients in C. grandiflora. Azafrin increases HO-1, NQO1, and Nrf2 expression. Azafrin shows cardioprotective effect against myocardial injury via activation of the Nrf2-ARE pathway. Azafrin can be used for research of cardiovascular diseases[1].
Product Specifications
CAS Number
[507-61-9]
UNSPSC
12352211
Target
Heme Oxygenase (HO) ; Keap1-Nrf2
Related Pathways
Metabolic Enzyme/Protease; NF-κB
Field of Research
Inflammation/Immunology; Cardiovascular Disease
Smiles
OC(/C=C/C(C)=C/C=C/C=C(C)/C=C/C=C(C)/C=C/[C@]1(C(C)(CCC[C@]1(O)C)C)O)=O
Molecular Formula
C27H38O4
Molecular Weight
426.59
References & Citations
[1]Yang S, et al. Cardioprotective role of azafrin in against myocardial injury in rats via activation of the Nrf2-ARE pathway. Phytomedicine. 2018 Aug 1;47:12-22.
Shipping Conditions
Room temperature
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-N15660/
Scientific Category
Natural Products
Clinical Information
No Development Reported
Curated Selection
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