Azafrin
Azafrin, a carotenoid, is one of the most abundant active ingredients in C. grandiflora. Azafrin increases HO-1, NQO1, and Nrf2 expression. Azafrin shows cardioprotective effect against myocardial injury via activation of the Nrf2-ARE pathway. Azafrin can be used for research of cardiovascular diseases[1].
Product Specifications
CAS Number
507-61-9
UNSPSC
12352211
Target
Heme Oxygenase (HO) ; Keap1-Nrf2
Related Pathways
Metabolic Enzyme/Protease; NF-κB
Field of Research
Inflammation/Immunology; Cardiovascular Disease
Smiles
OC(/C=C/C(C)=C/C=C/C=C(C)/C=C/C=C(C)/C=C/[C@]1(C(C)(CCC[C@]1(O)C)C)O)=O
Molecular Formula
C27H38O4
Molecular Weight
426.59
References & Citations
[1]Yang S, et al. Cardioprotective role of azafrin in against myocardial injury in rats via activation of the Nrf2-ARE pathway. Phytomedicine. 2018 Aug 1;47:12-22.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
E7444 96 Tests
LPO (Lipid Peroxlde/LactoperOxidase) Chicken ELISA Kit
Sign In for Pricing
View Details 
GTR15229511 1 Vial
Lentiviral mouse Atp5h shRNA (UAS) - Lentiviral mouse Atp5h shRNA (UAS, RFP) (25)
Sign In for Pricing
View Details 
CABT-47563MH 100 TEST
Mouse Anti Human Dectin-1 Monoclonal Antibody,RPE
Sign In for Pricing
View Details