Asperflavin
Asperflavin is an anti-inflammatory compound that can be produced by the marine fungus Eurotium amstelodami. Asperflavin inhibits the production of NO, PGE2, and proinflammatory cytokines, as well as the expression of inducible NOS (iNOS) in RAW 264.7 cells treated with LPS. Asperflavin can be used in the study of inflammatory diseases[1].
Product Specifications
CAS Number
1415764-41-8
UNSPSC
12352005
Target
Interleukin Related; NO Synthase; TNF Receptor
Related Pathways
Apoptosis; Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Smiles
OC1=C2C(C[C@](O)(CC2=O)C)=CC3=CC(O)=CC(OC)=C31
Molecular Formula
C16H16O5
Molecular Weight
288.30
References & Citations
[1]Yang, X, et al. Asperflavin, an Anti-Inflammatory Compound Produced by a Marine-Derived Fungus, Eurotium amstelodami. Molecules 2017, 22, 1823.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
IL-1; IL-6; iNOS; TNFRSF5/CD40
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