Withacoagin
Withacoagin is a withanolide that can be isolated from the roots of Withania coagulans. Withacoagin has various biological activites such as adaptogenic, anti-inflammatory, and antioxidant properties. Withacoagin regulates the activity of various enzymes and pathways related to oxidative stress and inflammation. Withacoagin can attenuates HIV-1 infection[1][2].
Product Specifications
CAS Number
119539-81-0
Product Name Alternative
(+) -Withacoagin
UNSPSC
12352005
Target
HIV
Related Pathways
Anti-infection
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Infection; Metabolic Disease; Inflammation/Immunology
Smiles
C[C@@]12[C@]3([H])[C@](C=C[C@]1(CC=CC2=O)O)([H])[C@@]4([H])[C@](CC3)([C@@](CC4)([H])[C@@](O)([C@@]5([H])CC(C)=C(C(O5)=O)C)C)C
Molecular Formula
C28H38O5
Molecular Weight
454.60
References & Citations
[1]Partha Neogi, et al., Withacoagin, a New Withanolide from Withania coagulans Roots, Bulletin of the Chemical Society of Japan, Volume 61, Issue 12, 1988. |[2]Jadaun P, et al., Withania somnifera extracts induced attenuation of HIV-1: a mechanistic approach to restrict viral infection. Virol J. 2023 Aug 3;20 (1) :173.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
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