Withacoagin

Withacoagin is a withanolide that can be isolated from the roots of Withania coagulans. Withacoagin has various biological activites such as adaptogenic, anti-inflammatory, and antioxidant properties. Withacoagin regulates the activity of various enzymes and pathways related to oxidative stress and inflammation. Withacoagin can attenuates HIV-1 infection[1][2].

Product Specifications

CAS Number

[119539-81-0]

Product Name Alternative

(+) -Withacoagin

UNSPSC

12352005

Target

HIV

Related Pathways

Anti-infection

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Infection; Metabolic Disease; Inflammation/Immunology

Smiles

C[C@@]12[C@]3([H])[C@](C=C[C@]1(CC=CC2=O)O)([H])[C@@]4([H])[C@](CC3)([C@@](CC4)([H])[C@@](O)([C@@]5([H])CC(C)=C(C(O5)=O)C)C)C

Molecular Formula

C28H38O5

Molecular Weight

454.60

References & Citations

[1]Partha Neogi, et al., Withacoagin, a New Withanolide from Withania coagulans Roots, Bulletin of the Chemical Society of Japan, Volume 61, Issue 12, 1988. |[2]Jadaun P, et al., Withania somnifera extracts induced attenuation of HIV-1: a mechanistic approach to restrict viral infection. Virol J. 2023 Aug 3;20 (1) :173.