Cassamine
Cassamine is a diterpenoid compound that can be isolated from the bark of Erythrophleum fordii. Cassamine exhibits certain cytotoxicity against non-small cell lung cancer cell lines, with IC50 values of 3.4, 2.1, and 1.9 μM against A549, NCI-H1975, and NCI-H1299, respectively. Cassamine has antitumor activity and can be used in the research of lung cancer and other tumors[1].
Product Specifications
CAS Number
[471-71-6]
UNSPSC
12352211
Target
Others
Related Pathways
Others
Field of Research
Cancer
Smiles
C[C@@]12[C@](CC([C@]3([H])[C@]2([H])CC/C([C@@H]3C)=C\C(OCCN(C)C)=O)=O)([H])[C@](C)(CCC1)C(OC)=O
Molecular Formula
C25H39NO5
Molecular Weight
433.58
References & Citations
[1]Ha MT, et al. Cytotoxic and apoptosis-inducing activities against human lung cancer cell lines of cassaine diterpenoids from the bark of Erythrophleum fordii. Bioorg Med Chem Lett. 2017 Jul 1;27 (13) :2946-2952.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Curated Selection
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