Melicopidine

Melicopidine (NSC 34757) is a DNA topoisomerase inhibitor, which is an acridone alkaloid found in the bark of Medicosma subsessilis. Melicopidine exerts potential antitumor activity by binding to DNA or inhibiting related enzyme activity[1].

Product Specifications

CAS Number

[475-91-2]

Product Name Alternative

NSC 34757

UNSPSC

12352005

Target

Topoisomerase

Related Pathways

Cell Cycle/DNA Damage

Field of Research

Cancer

Smiles

O=C1C2=C(N(C)C3=C(C4=C(C(OC)=C13)OCO4)OC)C=CC=C2

Molecular Formula

C17H15NO5

Molecular Weight

313.30

References & Citations

[1]Minh N T, et al. A New pyranoacridone alkaloid from the bark of Medicosma subsessilis (Rutaceae) [J]. ZEITSCHRIFT FUR NATURFORSCHUNG B, 2003, 58 (12) : 1234-1236.