Thalictoside

Thalictoside is found in A. squamosa L. Thalictoside is a sEH inhibitor (IC50: 20.2 µM) . Thalictoside exerts anti-osteoporotic effects through an estrogen-like mechanism. Thalictoside can be used in the research of cardiovascular and urinary diseases[1][2].

Product Specifications

CAS Number

[74213-96-0]

UNSPSC

12352005

Target

Epoxide Hydrolase

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Endocrinology; Metabolic Disease; Cardiovascular Disease

Smiles

O[C@H]1[C@H](O)[C@@H](O)[C@H](OC2=CC=C(CC[N+]([O-])=O)C=C2)O[C@@H]1CO

Molecular Formula

C14H19NO8

Molecular Weight

329.30

References & Citations

[1]Li, et al. Nitro derivatives and other compounds from sugar apple (Annona squamosa L.) leaves exhibit soluble epoxide hydrolase inhibitory activity. Med Chem Res 28, 1939–1944 (2019) .|[2]Xu F, et al. Anti-osteoporosis effect of Epimedium via an estrogen-like mechanism based on a system-level approach. J Ethnopharmacol. 2016 Jan 11;177:148-60.