Bi-magnolignan
Bi-magnolignan is a BRD4 inhibitor that induces DNA damage and apoptosis. Bi-magnolignan inhibits HCT116 cell proliferation with an IC50 value of 2.9 μM[1].
Product Specifications
CAS Number
[2883117-61-9]
UNSPSC
12352005
Target
Epigenetic Reader Domain
Related Pathways
Epigenetics
Field of Research
Cancer
Smiles
C=CCC1=C(O)C(O)=C(C2=C3C(OC4=C3C=C(CC=C)C=C4)=C(CC=C)C(O)=C2O)C5=C1OC6=CC=C(CC=C)C=C65
Molecular Formula
C36H30O6
Molecular Weight
558.62
References & Citations
[1]Zifeng Huang, et al. Discovery of Bi-magnolignan as a novel BRD4 inhibitor inducing apoptosis and DNA damage for cancer therapy. Biochem Pharmacol. 2025 May:235:116843.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Curated Selection
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