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Bi-magnolignan

Bi-magnolignan is a BRD4 inhibitor that induces DNA damage and apoptosis. Bi-magnolignan inhibits HCT116 cell proliferation with an IC50 value of 2.9 μM[1].

Product Specifications

CAS Number

2883117-61-9

UNSPSC

12352005

Target

Epigenetic Reader Domain

Related Pathways

Epigenetics

Field of Research

Cancer

Smiles

C=CCC1=C(O)C(O)=C(C2=C3C(OC4=C3C=C(CC=C)C=C4)=C(CC=C)C(O)=C2O)C5=C1OC6=CC=C(CC=C)C=C65

Molecular Formula

C36H30O6

Molecular Weight

558.62

References & Citations

[1]Zifeng Huang, et al. Discovery of Bi-magnolignan as a novel BRD4 inhibitor inducing apoptosis and DNA damage for cancer therapy. Biochem Pharmacol. 2025 May:235:116843.

Shipping Conditions

Room temperature

Scientific Category

Natural Products

Clinical Information

No Development Reported

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