Harzianoside B

Harzianoside B is a diterpene aminoglycoside compound discovered from Trichoderma sp. SCSIOW21. Harzianoside B has the activity of inhibiting the production of NO. In the experiment with macrophage RAW 264.7 cells, its IC50 value is close to the maximum tested concentration of 100 µM. It can be used in the research of the anti-inflammatory field[1].

Product Specifications

CAS Number

[3075431-10-3]

UNSPSC

12352211

Target

NO Synthase

Related Pathways

Immunology/Inflammation

Field of Research

Inflammation/Immunology

Smiles

OC/C(C[C@H](O[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1NC(C)=O)/C=C(C)/CC2)=C\C[C@H]3C(C)(C)C2=C(C)CC3

Molecular Formula

C28H45NO7

Molecular Weight

507.66

References & Citations

[1]Li H, et al. Novel Sesquiterpene and Diterpene Aminoglycosides from the Deep-Sea-Sediment Fungus Trichoderma sp. SCSIOW21. Mar Drugs. 2022 Dec 22;21 (1) :7.