Isopaucifloral F

Isopaucifloral F ((±) -Isopaucifloral F) is a Resveratrol (HY-16561) -derived sesquiterpenes. Isopaucifloral F is an orally active ERβ agonist (EC50: 46.96 μM) . Isopaucifloral F has antiosteoporosis activity. LD50 in rats: > 5 mg/kg[1][2].

Product Specifications

CAS Number

[1001259-00-2]

Product Name Alternative

(±) -Isopaucifloral F

UNSPSC

12352005

Target

Drug Derivative; Estrogen Receptor/ERR

Related Pathways

Others; Vitamin D Related/Nuclear Receptor

Field of Research

Inflammation/Immunology

Smiles

O=C1[C@@H](C2=CC(O)=CC(O)=C2)[C@H](C3=CC=C(C=C3)O)C4=C(O)C=C(O)C=C41

Molecular Formula

C21H16O6

Molecular Weight

364.35

References & Citations

[1]Sadia Faiz, et al. Synthetic strategies toward the synthesis of polyphenolic natural products: Pauciflorol F and isopaucifloral F: A review. Synthetic Communications. Volume 47, 2017-Issue 12. |[2]Hao XD, et al. Synthesis, estrogenic activity, and anti-osteoporosis effects in ovariectomized rats of resveratrol oligomer derivatives. Eur J Med Chem. 2015 Sep 18;102:26-38.