Isopaucifloral F
Isopaucifloral F ((±) -Isopaucifloral F) is a Resveratrol -derived sesquiterpenes. Isopaucifloral F is an orally active ERβ agonist (EC50: 46.96 μM). Isopaucifloral F has antiosteoporosis activity. LD50 in rats: > 5 mg/kg[1][2].
Product Specifications
CAS Number
1001259-00-2
Product Name Alternative
(±) -Isopaucifloral F
UNSPSC
12352005
Target
Drug Derivative; Estrogen Receptor/ERR
Related Pathways
Others; Vitamin D Related/Nuclear Receptor
Field of Research
Inflammation/Immunology
Smiles
O=C1[C@@H](C2=CC(O)=CC(O)=C2)[C@H](C3=CC=C(C=C3)O)C4=C(O)C=C(O)C=C41
Molecular Formula
C21H16O6
Molecular Weight
364.35
References & Citations
[1]Sadia Faiz, et al. Synthetic strategies toward the synthesis of polyphenolic natural products: Pauciflorol F and isopaucifloral F: A review. Synthetic Communications. Volume 47, 2017-Issue 12. |[2]Hao XD, et al. Synthesis, estrogenic activity, and anti-osteoporosis effects in ovariectomized rats of resveratrol oligomer derivatives. Eur J Med Chem. 2015 Sep 18;102:26-38.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
ERβ
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