Cryptolepinone
Cryptolepinone is a quinone reductase activator with a CD (concentration required to double induction) value of 0.02 μg/mL and can be found in Sida acuta. In the mouse mammary organ culture assay, 10 μg/mL of Cryptolepinone inhibited 83.3% of the preneoplastic lesions induced by DMBA. Cryptolepinone can be used in anti-cancer research[1].
Product Specifications
CAS Number
178884-07-6
UNSPSC
12352005
Target
Quinone Reductase
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cancer
Smiles
O=C1C2=C(N(C)C3=C1NC4=C3C=CC=C4)C=CC=C2
Molecular Formula
C16H12N2O
Molecular Weight
248.28
References & Citations
[1]Jang DS, et al. Compounds obtained from sida acuta with the potential to induce quinone reductase and to inhibit 7,12-dimethylbenz[a]anthracene-induced preneoplastic lesions in a mouse mammary organ culture model. Arch Pharm Res. 2003 Aug;26 (8) :585-90.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
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