Cryptolepinone

Cryptolepinone is a quinone reductase activator with a CD (concentration required to double induction) value of 0.02 μg/mL and can be found in Sida acuta. In the mouse mammary organ culture assay, 10 μg/mL of Cryptolepinone inhibited 83.3% of the preneoplastic lesions induced by DMBA (HY-W011845) . Cryptolepinone can be used in anti-cancer research[1].

Product Specifications

CAS Number

[178884-07-6]

UNSPSC

12352005

Target

Quinone Reductase

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Cancer

Smiles

O=C1C2=C(N(C)C3=C1NC4=C3C=CC=C4)C=CC=C2

Molecular Formula

C16H12N2O

Molecular Weight

248.28

References & Citations

[1]Jang DS, et al. Compounds obtained from sida acuta with the potential to induce quinone reductase and to inhibit 7,12-dimethylbenz[a]anthracene-induced preneoplastic lesions in a mouse mammary organ culture model. Arch Pharm Res. 2003 Aug;26 (8) :585-90.