Asperenone
Asperenone is an inhibitor of 15-lipoxygenase (15-LOX) with an IC50 value of 0.3 mM. It is also an inhibitor of platelet aggregation, with an IC50 value of 0.23 mM. Additionally, Asperenone has antifungal activity and can inhibit the growth of pathogenic fungi Ophiostoma crassivaginatum and O. piliferum. Asperenone can be used in the research of cardiovascular diseases and anti-infection fields[1].
Product Specifications
CAS Number
[18810-05-4]
UNSPSC
12352005
Target
Fungal; Lipoxygenase
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Field of Research
Infection; Cardiovascular Disease
Smiles
CCC(/C=C/C=C/C(C)=C/C=C/C=C/C1=CC=CC=C1)=O
Molecular Formula
C20H22O
Molecular Weight
278.39
References & Citations
[1]Sekhar Rao K C, et al. Asperenone: an inhibitor of 15-lipoxygenase and of human platelet aggregation from Aspergillus niger[J]. Biotechnology letters, 2002, 24: 1967-1970.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
15-LOX
Curated Selection
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