Deoxytopsentin
Deoxytopsentin is a compound that can be found in marine sponges. It is an inhibitor of pyruvate kinase (PK) in methicillin-resistant Staphylococcus aureus (MRSA), with an IC50 value of 240 nM. Deoxytopsentin can be used in research in the field of anti-infection [1].
Product Specifications
CAS Number
112515-42-1
UNSPSC
12352005
Target
Pyruvate Kinase
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Infection
Smiles
O=C(C1=CNC2=C1C=CC=C2)C3=NC=C(C4=CNC5=C4C=CC=C5)N3
Molecular Formula
C20H14N4O
Molecular Weight
326.35
References & Citations
[1]Veale CG, et al. Synthetic analogues of the marine bisindole deoxytopsentin: potent selective inhibitors of MRSA pyruvate kinase. J Nat Prod. 2015 Mar 27;78 (3) :355-62.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
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