Undulatine
Undulatine is a potent AChE inhibitor with an IC50 of 7.4 μM. Undulatine is able to cross the BBB by passive permeation and can be used in the study of Alzheimer’s disease[1].
Product Specifications
CAS Number
[6882-09-3]
UNSPSC
12352005
Target
Cholinesterase (ChE)
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Smiles
COC1=C(OCO2)C2=CC3=C1[C@@]4(CC5)C(C[C@@H](OC)[C@H]6[C@@H]4O6)[N@@]5C3
Molecular Formula
C18H21NO5
Molecular Weight
331.36
References & Citations
[1]Cahlíková L, et al. In Vitro Inhibitory Effects of 8-O-Demethylmaritidine and Undulatine on Acetylcholinesterase and Their Predicted Penetration across the Blood-Brain Barrier. J Nat Prod. 2015 Jun 26;78 (6) :1189-92.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Curated Selection
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