Undulatine

Undulatine is a potent AChE inhibitor with an IC50 of 7.4 μM. Undulatine is able to cross the BBB by passive permeation and can be used in the study of Alzheimer’s disease[1].

Product Specifications

CAS Number

[6882-09-3]

UNSPSC

12352005

Target

Cholinesterase (ChE)

Related Pathways

Neuronal Signaling

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Smiles

COC1=C(OCO2)C2=CC3=C1[C@@]4(CC5)C(C[C@@H](OC)[C@H]6[C@@H]4O6)[N@@]5C3

Molecular Formula

C18H21NO5

Molecular Weight

331.36

References & Citations

[1]Cahlíková L, et al. In Vitro Inhibitory Effects of 8-O-Demethylmaritidine and Undulatine on Acetylcholinesterase and Their Predicted Penetration across the Blood-Brain Barrier. J Nat Prod. 2015 Jun 26;78 (6) :1189-92.