Dihydrosamidin
Dihydrosamidin is a coumarin component isolated from the fruits of ammi visnaga. Dihydrosamidin promotes neuroplasticity, modulates glycolysis and oxidative phosphorylation and enhances antioxidant defences. Dihydrosamidin inhibits triacylglycerol accumulation in 3T3-L1 preadipocytes. Dihydrosamidin can be used for neuroprotective, anti-obesity study[1][2][3].
Product Specifications
CAS Number
6005-18-1
Product Name Alternative
Dimidin
UNSPSC
12352005
Target
Endogenous Metabolite
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Metabolic Disease; Neurological Disease
Smiles
CC(O[C@@H]1C2=C(OC(C)([C@@H]1OC(CC(C)C)=O)C)C=CC(C=C3)=C2OC3=O)=O
Molecular Formula
C21H24O7
Molecular Weight
388.41
References & Citations
[1]Winderl B, et al. Fast and improved separation of major coumarins in Ammi visnaga (L.) Lam. by supercritical fluid chromatography. J Sep Sci. 2016 Oct;39 (20) :4042-4048.|[2]Toropova AA, et al. Dihydrosamidin: the basic khellactone ester derived from Phlojodicarpus komarovii and its impact on neurotrophic factors, energy and antioxidant metabolism after rat cerebral ischemia-reperfusion injury. Nat Prod Res. 2024 Nov 27:1-6.|[3]Olennikov DN, et al. Khellactone Derivatives and Other Phenolics of Phlojodicarpus sibiricus (Apiaceae) : HPLC-DAD-ESI-QQQ-MS/MS and HPLC-UV Profile, and Antiobesity Potential of Dihydrosamidin. Molecules. 2019 Jun 19;24 (12) :2286.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Frequently Asked Questions
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