Visnaginone

Visnaginone is the derivative of Visnagin (HY-N1082) . Visnagin, an antioxidant furanocoumarin derivative, possess anti-inflammatory and analgesic properties. Visnagin has substantial potential to prevent Cerulein induced acute pancreatitis (AP) . Visnagin possess promising vasodilator effects in vascular smooth muscles[1][2][3].

Product Specifications

CAS Number

[484-27-5]

UNSPSC

12352005

Target

Drug Derivative

Related Pathways

Others

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology; Neurological Disease; Cardiovascular Disease

Smiles

CC(C1=C(O)C=C(OC=C2)C2=C1OC)=O

Molecular Formula

C11H10O4

Molecular Weight

206.19

References & Citations

[1]Abu-Hashem AA, et al. Synthesis of Novel Benzodifuranyl; 1,3,5-Triazines; 1,3,5-Oxadiazepines; and Thiazolopyrimidines Derived from Visnaginone and Khellinone as Anti-Inflammatory and Analgesic Agents. Molecules. 2020 Jan 5;25 (1) :220.|[2]Radim Vrzal, et al. Khellin and visnagin differentially modulate AHR signaling and downstream CYP1A activity in human liver cells. PLoS One. 2013 Sep 19;8 (9) :e74917. |[3]Lakshmi Priya Pasari, et al. Visnagin attenuates acute pancreatitis via Nrf2/NFκB pathway and abrogates associated multiple organ dysfunction. Biomed Pharmacother. 2019 Apr;112:108629.