Helminthosporol

Helminthosporol is a natural plant growth-regulator that can promote the growth of rice and lettuce seedlings. Helminthosporol can also inhibit the activity of acyl-CoA: cholesterol acyltransferase (ACAT) in rat liver microsomes and the synthesis of cholesterol esters in macrophages[1][2][3].

Product Specifications

CAS Number

[1619-29-0]

UNSPSC

12352211

Target

Acyltransferase; Phytohormone

Related Pathways

Metabolic Enzyme/Protease; Others

Field of Research

Metabolic Disease

Smiles

OC[C@H]1[C@@]2([H])C(C=O)=C([C@@]1(CC[C@@H]2C(C)C)C)C

Molecular Formula

C15H24O2

Molecular Weight

236.35

References & Citations

[1]Li YY, et al. Bioactive seco-Sativene Sesquiterpenoids from an Artemisia desertorum Endophytic Fungus, Cochliobolus sativus. J Nat Prod. 2020 May 22;83 (5) :1488-1494.|[2]Tamura S, et al. Isolation of helminthosporol as a natural plant growth-regulator and its chemical structure. Agricultural and Biological Chemistry, 1965, 29 (3) : 216-221.|[3]PARK J K O O, et al. Inhibition of acyl-CoA: cholesterol acyltransferase by helminthosporol and its related compounds. The Journal of Antibiotics, 1993, 46 (8) : 1303-1305.