Convolamine

Convolamine is an alkaloid found in Convolvulus pluricaulis and an effective positive modulator of the sigma-1 receptor (IC50 = 289 nM), exhibiting cognitive and neuroprotective properties[1][2].

Product Specifications

CAS Number

[500-56-1]

UNSPSC

12352005

Target

Sigma Receptor

Related Pathways

Neuronal Signaling

Field of Research

Neurological Disease

Smiles

O=C(C(C=C1)=CC(OC)=C1OC)O[C@H](C[C@]2([H])CC3)C[C@]3([H])N2C

Molecular Formula

C17H23NO4

Molecular Weight

305.37

References & Citations

[1]Gapparov A M, et al. Alkaloids of Convolvulus subhirsutus from Uzbekistan[J]. Chemistry of Natural Compounds, 2007, 43: 291-292.|[2]Crouzier L, et al. Convolamine, a tropane alkaloid extracted from Convolvulus plauricalis, is a potent sigma‐1 receptor‐positive modulator with cognitive and neuroprotective properties[J]. Phytotherapy Research, 2024, 38 (2) : 694-712.