Ferolin
Ferolin is the agonist for farnesoid X receptor (FXR) with an EC50 of 0.56 µM. Ferolin inhibits the expression of inflammatory genes (such as iNOS, IL-1β and TNFα) upon the FXR activation[1].
Product Specifications
CAS Number
[39380-12-6]
UNSPSC
12352005
Target
FXR
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Inflammation/Immunology
Smiles
O=C(C1=CC=C(C=C1)O)OC2C/C(C)=C/CCC(/C=C/C2C(C)C)(C)O
Molecular Formula
C22H30O4
Molecular Weight
358.47
References & Citations
[1]Zheng W, et al., A Novel Class of Natural FXR Modulators with a Unique Mode of Selective Co-regulator Assembly. Chembiochem. 2017 Apr 18;18 (8) :721-725.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Curated Selection
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