Acremorin E
Acremorin E (Compound 7) is a terpenoid compound with antifungal activity. Acremorin E exerts its anti-C. gattiii effect by upregulating genes related to biosynthesis and RNA binding of ribosomes, as well as inhibiting RNA and nucleic acid metabolism and ATPase activity (MIC: 8 μg/mL) [1].
Product Specifications
UNSPSC
12352005
Target
Fungal
Related Pathways
Anti-infection
Field of Research
Infection
Smiles
CC1=C(C(O)=C(C(O)=C1Cl)C/C=C([C@H](C[C@]2([C@@H](CCC([C@@H]2C)=O)C)C)O)\C)C=O
Molecular Formula
C23H31ClO5
Molecular Weight
422.94
References & Citations
[1]Huo R, et al. Halogenated meroterpenoids with antifungal activities from the Deep-Sea-Derived fungus Acremonium sclerotigenum guided by the genomic and OSMAC strategy. Bioorg Chem. 2025 Mar;156:108186.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
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