Capuramycin

Capuramycin is an antibacterial agent, translocase I (MurX/MraY) inhibitor, with an IC50 of 0.127 μM against MurX. Capuramycin has antibacterial activity against M. tuberculosis[1].

Product Specifications

CAS Number

[102770-00-3]

UNSPSC

12352005

Target

Bacterial

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Smiles

NC([C@@H]([C@](O[C@@H](N(C=CC1=O)C(N1)=O)[C@@H]2O)([H])[C@H]2OC)O[C@H]([C@H]3O)OC(C(N[C@@H](CCCCN4)C4=O)=O)=C[C@@H]3O)=O

Molecular Formula

C23H31N5O12

Molecular Weight

569.52

References & Citations

[1]Siricilla S, et al. Discovery of a capuramycin analog that kills nonreplicating Mycobacterium tuberculosis and its synergistic effects with translocase I inhibitors. J Antibiot (Tokyo) . 2015 Apr;68 (4) :271-8.