Betavulgarin

Betavulgarin is an anticancer agent. Betavulgarin can be isolated from Sugar Beet (Beta vulgaris) . Betavulgarin suppresses the proliferation, migration, colony formation, and mammosphere formation of breast cancer cells, and reduces the size of the CD44+/CD24− subpopulation and the expression of the self-renewal- related genes C-Myc, Nanog and Oct4. Betavulgarin promotes BCSCs death through the regulation of Stat3/Sox2 signaling[1].

Product Specifications

CAS Number

[51068-94-1]

UNSPSC

12352005

Target

STAT

Related Pathways

JAK/STAT Signaling; Stem Cell/Wnt

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Smiles

O=C1C(C2=C(O)C=CC=C2)=COC3=C1C(OC)=C4OCOC4=C3

Molecular Formula

C17H12O6

Molecular Weight

312.27

References & Citations

[1]Liu R, et al. Betavulgarin Isolated from Sugar Beet (Beta vulgaris) Suppresses Breast Cancer Stem Cells through Stat3 Signaling. Molecules. 2020 Jun 30; 25 (13) :2999.