Arphamenine B
Arphamenine B is a Zn2+-dependent exopeptidase that selectively removes arginine and/or lysine residues from the NH2-terminus of several peptide substrates. Arphamenine B is an inhibitor of aminopeptidase B that can be isolated from bacteria. Arphamenine B enhances the immune response and is used to characterize novel proteases[1][2][3].
Product Specifications
CAS Number
88465-81-0
UNSPSC
12352005
Target
Bacterial
Related Pathways
Anti-infection
Field of Research
Infection
Smiles
N=C(N)NCCC[C@H](N)C(C[C@H](C(O)=O)CC1=CC=C(C=C1)O)=O.Cl
Molecular Formula
C16H25ClN4O4
Molecular Weight
372.85
References & Citations
[1]Foulon T, et al. Aminopeptidase B (EC 3.4.11.6) . Int J Biochem Cell Biol. 1999 Jul;31 (7) :747-50.|[2]Umezawa H, et al. Arphamenines A and B, new inhibitors of aminopeptidase B, produced by bacteria. J Antibiot (Tokyo) . 1983 Nov;36 (11) :1572-5.|[3]Kubo H, et al. Involvement of sperm proteases in the binding of sperm to the vitelline envelope in Xenopus laevis. Zoolog Sci. 2008 Jan;25 (1) :80-7.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Frequently Asked Questions
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