Herbimycin B

Herbimycin B is an ansamycin antibiotic that acts as a Src family kinase inhibitor. Herbimycin B has herbicidal effect on most monocotyledons and dicotyledons, inhibits the activity of tobacco Mosaic virus (TMV), HeLa cells and Ehrlich cells[1].

Product Specifications

CAS Number

[76207-83-5]

UNSPSC

12352005

Target

Antibiotic; Bacterial; Src

Related Pathways

Anti-infection; Protein Tyrosine Kinase/RTK

Field of Research

Cancer; Infection

Smiles

C/C1=C\[C@@H]([C@H]([C@H](C[C@H](C)CC(C(C(NC(/C(C)=C/C=C\[C@@H]([C@H]1OC(N)=O)OC)=O)=C2)=O)=CC2=O)OC)C)C

Molecular Formula

C29H40N2O7

Molecular Weight

528.64

References & Citations

[1]Y Iwai, et al. Herbimycin B, a new benzoquinonoid ansamycin with anti-TMV and herbicidal activities. J Antibiot (Tokyo) . 1980 Oct;33 (10) :1114-9.