1-Hydroxyoxaunomycin
1-Hydroxyoxaunomycin is an antibiotic. 1-Hydroxyoxaunomycin inhibits U210 cell growth, DNA synthesis and RNA synthesis with IC50 of 0.0005 μg/mL, 1.00 μg/mL and 0.76 μg/mL respectively[1].
Product Specifications
CAS Number
145165-10-2
UNSPSC
12352005
Target
Antibiotic; Bacterial; DNA/RNA Synthesis
Related Pathways
Anti-infection; Cell Cycle/DNA Damage
Field of Research
Cancer; Infection
Smiles
O=C1C2=C(C(C3=C1C(O)=C([C@H]([C@@](CC)(C[C@@H]4O[C@@H]5O[C@H]([C@H]([C@H](C5)N)O)C)O)O)C4=C3O)=O)C(O)=CC=C2O
Molecular Formula
C26H29NO11
Molecular Weight
531.51
References & Citations
[1]A Yoshimoto, et al. Production of new anthracycline antibiotics 1-hydroxy-oxaunomycin and 6-deoxyoxaunomycin by limited biosynthetic conversion using a daunorubicin-negative mutant. J Antibiot (Tokyo) . 1992 Oct;45 (10) :1609-17.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
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