1-Hydroxyoxaunomycin

1-Hydroxyoxaunomycin is an antibiotic. 1-Hydroxyoxaunomycin inhibits U210 cell growth, DNA synthesis and RNA synthesis with IC50 of 0.0005 μg/mL, 1.00 μg/mL and 0.76 μg/mL respectively[1].

Product Specifications

CAS Number

[145165-10-2]

UNSPSC

12352005

Target

Antibiotic; Bacterial; DNA/RNA Synthesis

Related Pathways

Anti-infection; Cell Cycle/DNA Damage

Field of Research

Cancer; Infection

Smiles

O=C1C2=C(C(C3=C1C(O)=C([C@H]([C@@](CC)(C[C@@H]4O[C@@H]5O[C@H]([C@H]([C@H](C5)N)O)C)O)O)C4=C3O)=O)C(O)=CC=C2O

Molecular Formula

C26H29NO11

Molecular Weight

531.51

References & Citations

[1]A Yoshimoto, et al. Production of new anthracycline antibiotics 1-hydroxy-oxaunomycin and 6-deoxyoxaunomycin by limited biosynthetic conversion using a daunorubicin-negative mutant. J Antibiot (Tokyo) . 1992 Oct;45 (10) :1609-17.