Propeptin
Propeptin is a peptide antibiotic composed of 19 amino acids. Propeptin has weaker activity against Pseudomonas aeruginosa, Mycobacterium monobacterium, and Xanthomonas oryzae. Propeptin has no effect on KB and L1210 cells of tumor cell lines, but has an inhibitory effect on prolyl endopeptidase[1].
Product Specifications
CAS Number
146764-30-9
UNSPSC
12352005
Target
Antibiotic; Bacterial
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Smiles
O=C([C@@]1([H])N(CCC1)C([C@@H](NC(CNC(C[C@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC2=O)CC3=CNC4=CC=CC=C34)=O)CC(O)=O)=O)CC5=CC=C(C=C5)O)=O)CCCNC(N)=N)=O)C(N[C@@H](CC(C)C)C(N[C@H](C(NCC(NCC(N[C@H](C(N[C@@H]([C@H](O)C)C(N[C@H](C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CO)C(N6[C@@H](CCC6)C(O)=O)=O)=O)=O)CC7=CC=CC=C7)=O)=O)CC8=CN=CN8)=O)=O)=O)CC9=CC=CC=C9)=O)=O)=O)=O)CC%10=CC=C(C=C%10)O)=O)N[C@H]2CC%11=CNC%12=CC=CC=C%11%12
Molecular Formula
C113H142N26O27
Molecular Weight
2296.49
References & Citations
[1]Ken-ichi Kimura, et al. Novel propeptin analog, propeptin-2, missing two amino acid residues from the propeptin C-terminus loses antibiotic potency. J Antibiot (Tokyo) . 2007 Aug;60 (8) :519-23.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Frequently Asked Questions
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