Espicufolin
Espicufolin is a neuroprotective substance that can be found in Streptomyces sp:cu39. Espicufolin can inhibit glutamate toxicity, thereby reducing or overcoming cerebral ischemic damage, with a toxicity EC50 value of 40 nM for N18-RE-105 cells. Espicufolin can be used in the study of neurodegenerative diseases[1].
Product Specifications
CAS Number
[182232-96-8]
UNSPSC
12352211
Target
Others
Related Pathways
Others
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Smiles
O=C1C2=C(C(C3=CC=CC(O)=C31)=O)C=C(CO)C4=C2OC([C@H](C)CC)=CC4=O
Molecular Formula
C22H18O6
Molecular Weight
378.37
References & Citations
[1]J S Kim, et al. A novel neuronal cell protecting substance, espicufolin, produced by Streptomyces sp. cu39. J Antibiot (Tokyo) . 1996 Sep;49 (9) :947-8.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Curated Selection
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