Clavariopsin A

Clavariopsin A is a cyclic depsipeptide antibiotic. Clavariopsin A shows antifungal activity for Candida albicans IFO 0583, Candida albicans ATCC 10231, Aspergillus niger AJ117374, Aspergillus fumigatus AJ117190, Aspergillus fumigatus JCM1739 with MIC values of 8, 8, 16, 2, 4 μg/mL, respectively[1].

Product Specifications

CAS Number

[227083-47-8]

UNSPSC

12352005

Target

Antibiotic; Fungal

Related Pathways

Anti-infection

Smiles

O=C1[C@@]2([H])N(CCCC2)C([C@H](OC([C@@H](NC([C@@H](N(C(CNC([C@](N(C([C@](N(C([C@@H](N(C([C@@H](NC([C@@H](N1C)C(C)C)=O)C(C)C)=O)C)CC(O)=O)=O)C)([H])[C@@H](C)CC)=O)C)([H])[C@@H](C)CC)=O)=O)C)C(C)C)=O)CC3=CC=C(C=C3)OC)=O)C(C)C)=O

Molecular Formula

C59H95N9O14

Molecular Weight

1154.44

References & Citations

[1]Kaida K, et al. New cyclic depsipeptide antibiotics, clavariopsins A and B, produced by an aquatic hyphomycetes, Clavariopsis aquatica. 1. Taxonomy, fermentation, isolation, and biological properties. J Antibiot (Tokyo) . 2001 Jan;54 (1) :17-21.