Clavicoronic acid

Clavicoronic acid is an avian myeloblastosis virus and Moloney murine leukemia virus reverse transcriptases inhibitor with Ki values of 130, 68 µM, respectively. Clavicoronic acid inhibits the multiplication of vesicular stomatitis virus by interfering with this virus's RNA-directed RNA-polymerase. Clavicoronic acid shows no cytotoxicity[1].

Product Specifications

CAS Number

[139748-98-4]

UNSPSC

12352211

Target

DNA/RNA Synthesis

Related Pathways

Cell Cycle/DNA Damage

Field of Research

Infection

Smiles

CC1=C(C(C(O)=O)=O)C(C=O)=C[C@@]2([H])[C@]1([H])CC(C)(C)C2

Molecular Formula

C15H18O4

Molecular Weight

262.30

References & Citations

[1]Erkel G, et al. Antibiotics from basidiomycetes. XLI. Clavicoronic acid, a novel inhibitor of reverse transcriptases from Clavicorona pyxidata (Pers. ex Fr.) Doty. J Antibiot (Tokyo) . 1992 Jan;45 (1) :29-37.