Pterulinic acid

Pterulinic acid is a coenzyme I: Coenzyme Q oxidoreductase inhibitor. he IC50 (μg/mL) L1210 and HL60 of Pterulinic acid to mammalian cell lines are 50 and 20 respectively. HeLaS3 25; BHK is 100[1].

Product Specifications

CAS Number

[190143-30-7]

UNSPSC

12352005

Target

Quinone Reductase

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Cancer

Smiles

OC(CC1=CC2=CC(C=C/C(CO3)=C\Cl)=C3C=C2O1)=O

Molecular Formula

C15H11ClO4

Molecular Weight

290.70

References & Citations

[1]M Engler, et al. Pterulinic acid and pterulone, two novel inhibitors of NADH:ubiquinone oxidoreductase (complex I) produced by a Pterula species. II. Physico-chemical properties and structure elucidation. J Antibiot (Tokyo) . 1997 Apr;50 (4) :330-3.