Phleomycin G
Phleomycin G is a heteropeptide antibiotic. Phleomycin G has anti-Gram-positive bacteria, negative bacteria and mycobacterium effects. Phleomycin G extends the survival time of mice transplanted with Ehrman's ascites cancer. Phleomycin G inhibits airy entity carcinoma in mice[1].
Product Specifications
CAS Number
[11031-15-5]
UNSPSC
12352211
Target
Antibiotic; Bacterial
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Infection
Smiles
O=C(N)OC1C(C(OC2C(OC(C(C2O)O)CO)OC(C(C(NC(C(C(C)C(NC(C(C)O)C(NCCC3=NC(CS3)C4=NC(C(NCCCCNC(NCCCCNC(NCCCCNC(N)=N)=N)=N)=O)=CS4)=O)=O)O)C)=O)NC(C5=NC(C(CC(N)=O)NCC(C(N)=O)N)=NC(N)=C5C)=O)C6=CN=CN6)OC(C1O)CO)O
Molecular Formula
C65H108N26O21S2
Molecular Weight
1653.84
References & Citations
[1]James B Wilson, et al. Several tetratricopeptide repeat (TPR) motifs of FANCG are required for assembly of the BRCA2/D1-D2-G-X3 complex, FANCD2 monoubiquitylation and phleomycin resistance. Mutat Res. 2010 Jul 7;689 (1-2) :12-20.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Curated Selection
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