Phleomycin E
Phleomycin E is a heteropeptide antibiotic. Phleomycin E has anti-Gram-positive bacteria, negative bacteria and mycobacterium effects. Phleomycin E extends the survival time of mice transplanted with Ehrman's ascites cancer. Phleomycin E inhibits airy entity carcinoma in mice with an IC50 of 0.31 μg/mL[1].
Product Specifications
CAS Number
[11031-13-3]
UNSPSC
12352005
Target
Antibiotic; Bacterial
Related Pathways
Anti-infection
Field of Research
Cancer; Infection
Smiles
O=C(N)OC1C(C(OC2C(OC(C(C2O)O)CO)OC(C(C(NC(C(C(C)C(NC(C(C)O)C(NCCC3=NC(CS3)C4=NC(C(NCCCCNC(NCCCCNC(N)=N)=N)=O)=CS4)=O)=O)O)C)=O)NC(C5=NC(C(CC(N)=O)NCC(C(N)=O)N)=NC(N)=C5C)=O)C6=CN=CN6)OC(C1O)CO)O
Molecular Formula
C60H97N23O21S2
Molecular Weight
1540.68
References & Citations
[1]R M Hall, et al. Identification and mapping of regions of the plasmid pKM101 which influence the growth rate and resistance to phleomycin E of Escherichia coli WP2. J Bacteriol. 1985 Sep;163 (3) :1142-6.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Curated Selection
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