Demethylmacrocin

Demethylmacrocin is a key intermediate in the biosynthetic pathway of Tylosin (HY-B0519A) . Demethylmacrocin can be efficiently converted into tylosin through specific sequential oxidation and methylation reactions[1][2].

Product Specifications

CAS Number

[79404-98-1]

UNSPSC

12352005

Target

Drug Intermediate

Related Pathways

Others

Field of Research

Others

Smiles

O=CCC1CC(C)C(/C=C\C(C)=C\C(C(CC)OC(CC(C(C1OC2OC(C(C(C2O)N(C)C)OC3OC(C(C(C)(C3)O)O)C)C)C)O)=O)COC4OC(C(C(C4O)O)O)C)=O

Molecular Formula

C44H73NO17

Molecular Weight

888.05

References & Citations

[1]Kim E, et al. Characterization of the Two Methylation Steps Involved in the Biosynthesis of Mycinose in Tylosin. J Nat Prod. 2016 Aug 26;79 (8) :2014-21.|[2]Baltz RH, et al. Biosynthesis of the macrolide antibiotic tylosin. A preferred pathway from tylactone to tylosin. J Antibiot (Tokyo) . 1983 Feb;36 (2) :131-41.