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Laccaridione B

Laccaridione B can inhibit the activity of antiserine protease. Laccaridione B inhibits trypsin, papain, thermophilic protease, collagenase and zinc protease with IC50s of 10.9 μg/mL, 5.1 μg/mL, 8.4 μg/mL, 5.7 μg/mL and 3.0 μg/mL, respectively. Laccaridione B also has a strong anti-proliferative activity against L-929, K-562 and HeLa cells with IC50s of 2.4 μg/mL, 1.8 μg/mL and 13.9 μg/mL, respectively[1].

Product Specifications

CAS Number

320369-81-1

UNSPSC

12352005

Target

Ser/Thr Protease

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Cancer; Infection

Smiles

CCOC1C2=C(C=C(O1)/C(C)=C/C(C)CC)C=C3C(C(C(C(OC)=C3)=O)=O)=C2O

Molecular Formula

C23H26O6

Molecular Weight

398.45

References & Citations

[1]Barbara Falkensammer, et al. Basidiomycete metabolites attenuate virulence properties of Candida albicans in vitro. Mycoses. 2008 Nov;51 (6) :505-14.

Shipping Conditions

Room temperature

Scientific Category

Natural Products

Clinical Information

No Development Reported

Frequently Asked Questions

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