Laccaridione B
Laccaridione B can inhibit the activity of antiserine protease. Laccaridione B inhibits trypsin, papain, thermophilic protease, collagenase and zinc protease with IC50s of 10.9 μg/mL, 5.1 μg/mL, 8.4 μg/mL, 5.7 μg/mL and 3.0 μg/mL, respectively. Laccaridione B also has a strong anti-proliferative activity against L-929, K-562 and HeLa cells with IC50s of 2.4 μg/mL, 1.8 μg/mL and 13.9 μg/mL, respectively[1].
Product Specifications
CAS Number
320369-81-1
UNSPSC
12352005
Target
Ser/Thr Protease
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cancer; Infection
Smiles
CCOC1C2=C(C=C(O1)/C(C)=C/C(C)CC)C=C3C(C(C(C(OC)=C3)=O)=O)=C2O
Molecular Formula
C23H26O6
Molecular Weight
398.45
References & Citations
[1]Barbara Falkensammer, et al. Basidiomycete metabolites attenuate virulence properties of Candida albicans in vitro. Mycoses. 2008 Nov;51 (6) :505-14.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
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