2-Hydroxyaclacinomycin B

2-Hydroxyaclacinomycin B is an anthracycline antibiotic. 2-Hydroxyaclacinomycin B can be found in Strptomyces galilaeus A-862 (FERM BP-45) . 2-Hydroxyaclacinomycin B inhibits RNA synthesis and has anti-tumor activity[1].

Product Specifications

CAS Number

[85819-82-5]

UNSPSC

12352005

Target

Bacterial

Related Pathways

Anti-infection

Field of Research

Cancer

Smiles

O=C1C2=C(C(O)=CC(O)=C2)C(C3=C1C=C(C4=C3O)[C@@H](C(OC)=O)[C@@](O)(CC)C[C@@H]4O[C@@H]5O[C@H]([C@H]([C@H](C5)N(C)C)O[C@@H]6O[C@H]([C@H]7O[C@H](OC(C(C8)=O)C)[C@H]8O[C@H]7C6)C)C)=O

Molecular Formula

C42H51NO16

Molecular Weight

825.85

References & Citations

[1]Yoshimoto A, et al. Anthracycline antibiotic 2-hydroxyaclacinomycins. II. Production of 2-hydroxyaclacinomycins A and B by a new recombinant strain and their antitumor activities. Jpn J Antibiot. 1991 Mar;44 (3) :277-86.