6"'-Deamino-6"'-hydroxyparomomycin I

6"'-Deamino-6"'-hydroxyparomomycin I is an amino glycosyl antibiotic that can be produced by Streptomyces rimosus forma paromomycinus A67 15. It is active against both Gram-positive and Gram-negative bacteria. 6"'-Deamino-6"'-hydroxyparomomycin I can be used as an intermediate in the biosynthesis of paromomycin[1][2].

Product Specifications

CAS Number

[78524-72-8]

UNSPSC

12352005

Target

Antibiotic; Bacterial

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Smiles

O[C@H]([C@@H]([C@H](O1)CO)O[C@H]2O[C@H]([C@H]([C@@H]([C@H]2N)O)O)CO)[C@@H]1O[C@H]([C@H]([C@@H](C[C@@H]3N)N)O)[C@@H]3O[C@H]4O[C@@H]([C@H]([C@@H]([C@H]4N)O)O)CO

Molecular Formula

C23H44N4O15

Molecular Weight

616.61

References & Citations

[1]Autissier D, et al. 6"'-Deamino-6"'-hydroxy derivatives, as intermediates in the biosynthesis of neomycin and paromomycin. J Antibiot (Tokyo) . 1981 May;34 (5) :536-43.|[2]Toda S, NAKAGAWA S, NAITO T, et al. AMINOGLYCOSIDE ANTIBIOTICS. XV CHEMICAL CONVERSION OF NEOMYCIN B TO PAROMOMYCIN I, 6'''-DEAMINO-6'''-HYDROXYNEOMYCIN B AND 6'''-DEAMINO-6'''-HYDROXY-PAROMOMYCIN I. The Journal of Antibiotics, 1983, 36 (1) : 87-91.