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Lactonamycin

Lactonamycin had strong activity against Gram-positive bacteria including Staphylococcus, Streptococcus, Enterococcus, MRSA (MIC of 0.39-0.78 μg/mL) and VRE (MIC of 0.39-0.78 μg/mL) . Lactonamycin also has inhibitory effect on L-1210, P388, S180, FS-3, Ehrlich, B16-BL5 and other tumor cell lines (IC50s of 0.06-3.3 μg/mL) [1].

Product Specifications

CAS Number

182234-02-2

UNSPSC

12352005

Target

Bacterial

Related Pathways

Anti-infection

Field of Research

Cancer; Infection

Smiles

CO[C@](OC1)(CC(O2)=O)[C@]2(C(C(C(C3=O)=CC4=C5)=C(O)C4=C6C(C(N(C6)C)=O)=C5O)=O)[C@@]13O[C@@H]7O[C@H]([C@H](CC7)O)C

Molecular Formula

C28H27NO12

Molecular Weight

569.51

References & Citations

[1]Philip J Parsons, et al. An Approach to the Core of Lactonamycin. Org Lett. 2017 May 19;19 (10) :2533-2535.

Shipping Conditions

Room temperature

Scientific Category

Natural Products

Clinical Information

No Development Reported

Frequently Asked Questions

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