Lactonamycin
Lactonamycin had strong activity against Gram-positive bacteria including Staphylococcus, Streptococcus, Enterococcus, MRSA (MIC of 0.39-0.78 μg/mL) and VRE (MIC of 0.39-0.78 μg/mL) . Lactonamycin also has inhibitory effect on L-1210, P388, S180, FS-3, Ehrlich, B16-BL5 and other tumor cell lines (IC50s of 0.06-3.3 μg/mL) [1].
Product Specifications
CAS Number
[182234-02-2]
UNSPSC
12352005
Target
Bacterial
Related Pathways
Anti-infection
Field of Research
Cancer; Infection
Smiles
CO[C@](OC1)(CC(O2)=O)[C@]2(C(C(C(C3=O)=CC4=C5)=C(O)C4=C6C(C(N(C6)C)=O)=C5O)=O)[C@@]13O[C@@H]7O[C@H]([C@H](CC7)O)C
Molecular Formula
C28H27NO12
Molecular Weight
569.51
References & Citations
[1]Philip J Parsons, et al. An Approach to the Core of Lactonamycin. Org Lett. 2017 May 19;19 (10) :2533-2535.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
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