Hedamycin
Hedamycin is a quinone antibiotic. Hedamycin has anti-Gram-positive bacteria, negative bacterium, mycobacterium and yeast fungus activity (MIC is 0.031-3.2 μg/mL) . 0.8 μg/mL of Hedamycin can inhibit Tetrahymena pyriformis. Hedamycin also can inhibit rat duodenum adenocarcinoma, rats Walker 256 tumor (50 μg/kg/day), HeLa cell (IG50 is 0.00013 μg/mL), e. coli lysogenic W1709 (λ) phage (MIC is 0.0125 μg/mL) [1].
Product Specifications
CAS Number
11048-97-8
UNSPSC
12352005
Target
Antibiotic; Bacterial
Related Pathways
Anti-infection
Field of Research
Infection
Smiles
[H][C@@]1(O[C@H]1C)[C@@]2(O[C@]2(C3=CC(C4=C(C5=C(C(C6=C(C(O)=C(C=C6[C@H]7C[C@H]([C@@H]([C@H](O7)C)O)N(C)C)[C@H]8C[C@](N(C)C)([C@@H]([C@@H](O8)C)O)C)C5=O)=O)C=C4C)O3)=O)C)[H]
Molecular Formula
C41H50N2O11
Molecular Weight
746.84
References & Citations
[1]Lan Chun Tu, et al. Hedamycin, a DNA alkylator, induces (gamma) H2AX and chromosome aberrations: involvement of phosphatidylinositol 3-kinase-related kinases and DNA replication fork movement. Mol Cancer Ther. 2005 Aug;4 (8) :1175-85.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
K4843408 1.0 µg DNA
Apoc2 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 3)
Sign In for Pricing
View Details 
038696-PE 200 µL
MUDEN, CT (AP5M1, C14orf108, MUDENG, AP-5 complex subunit mu-1, Adapter-related protein complex 5 mu subunit, Mu-2-related death-inducing protein, Putative HIV-1 infection-related protein) (PE) discontinued
Sign In for Pricing
View Details