Griseolic acid B

Griseolic acid B (7′-Desoxygriseolic acid) has the activity of inhibiting cyclic adenosine monophosphate (cAMP) phosphodiesterase [EC 3.1.4.17] with an IC50 of 0.16 μM[1].

Product Specifications

CAS Number

[98890-01-8]

Product Name Alternative

7′-Desoxygriseolic acid

UNSPSC

12352005

Target

Phosphodiesterase (PDE)

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Neurological Disease

Smiles

NC1=NC=NC2=C1N=CN2[C@@H]3OC4=C[C@](C(O)=O)(O[C@]4([C@]3(O)[H])[H])CC(O)=O

Molecular Formula

C14H13N5O7

Molecular Weight

363.28

References & Citations

[1]S Takahashi, et al. Griseolic acids B and C, an inhibitor of cyclic adenosine 3',5'-monophosphate phosphodiesterase. J Antibiot (Tokyo) . 1988 May;41 (5) :705-6.