Ocinaplon
Ocinaplon (DOV 273547) is a partial GABAA receptor positive allosteric modulator with relatively high efficacy at the α1 subunit[1].
Product Specifications
CAS Number
[96604-21-6]
Product Name Alternative
DOV 273547
UNSPSC
12352005
Target
GABA Receptor
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ocinaplon.html
Purity
99.70
Solubility
DMSO : 2 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(C1=NC=CC=C1)C2=C3N=CC=C(C4=CC=NC=C4)N3N=C2
Molecular Formula
C17H11N5O
Molecular Weight
301.30
References & Citations
[1]Christiaan H Vinkers, et al. Discriminative Stimulus Properties of GABAA Receptor Positive Allosteric Modulators TPA023, Ocinaplon and NG2-73 in Rats Trained to Discriminate Chlordiazepoxide or Zolpidem. Eur J Pharmacol. 2011 Oct 1;668 (1-2) :190-3.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
Phase 3
Available Sizes
Curated Selection
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