Cycloepoxydon

Cycloepoxydon inhibits the Phorbol 12-myristate 13-acetate (HY-18739) (PMA) -induced NF-KB and AP-1 mediated secreted alkaline phosphatase (SEAP) expression with IC50s of 1-2 μg/mL (4.2-8.4 μM) and 3-5 μg/mL (12.6-21 μM), respectively[1].

Product Specifications

CAS Number

[193481-66-2]

UNSPSC

12352005

Target

Phosphatase

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Inflammation/Immunology

Smiles

O[C@@H]1C2=C(CO[C@H]([C@@H]2O)CCC)C([C@]3([H])[C@@]1([H])O3)=O

Molecular Formula

C12H16O5

Molecular Weight

240.25

References & Citations

[1]A Gehrt, et al. Cycloepoxydon, 1-hydroxy-2-hydroxymethyl-3-pent-1-enylbenzene and 1-hydroxy-2-hydroxymethyl-3-pent-1,3-dienylbenzene, new inhibitors of eukaryotic signal transduction. J Antibiot (Tokyo) . 1998 May;51 (5) :455-63.