Concanamycin F

Concanamycin F has antifungal, antiviral, immunosuppressive, cytotoxic and other activities, and is a specific inhibitor of V-type ATPase (Ki=0.02 nM), which is an important tool for biochemical research[1].

Product Specifications

CAS Number

[144539-92-4]

UNSPSC

12352005

Target

Fungal

Related Pathways

Anti-infection

Field of Research

Infection

Smiles

O=C1O[C@H]([C@@H](C)[C@@H](O)[C@@H]([C@@]2(O)C[C@@H](O)[C@H](C)[C@@H](/C=C/C)O2)C)[C@@H](OC)/C=C/C=C(C)/C[C@@H](C)[C@H](O)[C@H](CC)[C@H](O)[C@H](C)/C=C(C)/C=C1\OC

Molecular Formula

C39H64O10

Molecular Weight

692.92

References & Citations

[1]I Paterson I, et al. Total Synthesis of (+) -Concanamycin F We thank the EPSRC (GR/K54052), Knoll Pharmaceuticals (CASE Studentship to V.A.D.), the Cambridge Commonwealth Trust (M.D.M.), and Merck for support, and Dr R. Norrie (Knoll Pharmaceuticals) for helpful discussions. We also thank Prof. A. Zeeck (Göttingen) for kindly providing copies of (1) H NMR spectra of concanamycin F (concanolide A) . Angew Chem Int Ed Engl. 2000 Apr;39 (7) :1308-1312.